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BioLactobionic Acid

BioLactobionic Acid

Lactobionic Acid is an oxidized form of lactose extracted from milk, and is a cosmetic ingredient that can be used safely in all skin types because it is naturally produced in the body. Lactobionic Acid (LBA) consists of a glycolic acid molecule and a galactose molecule. and it’s known to be the mildest exfoliating ingredients such as AHA BHA.

 

In terms of exfoliating effectiveness, LBA(Lactobionic Acid) has a larger molecular size than Alpha Hydroxy Acid (AHA) and Beta Hydroxy Acid (BHA) and such size differences make LBA slowly absorbs into the skin and stand as a hypoallergenic exfoliator, namely knowns as a third-generation for exfoliating which gets absorbed into the skin without irritating the skin.

 

LBA(Lactobionic Acid) has a large number of hydroxyl groups, which makes it absorb moisture in the atmosphere and form a natural gel matrix on the skin. At the same time, LBA not only works to exfoliate the skin but work to moisturize the skin long-term which keeps the skin softer, brighter, and healthier.

 

GF Fermentech's BioLactobionic Acid is a 100% natural material produced through the proprietary fermentation process. Its clinical test in human subjects has proven its excellence in exfoliation, moisturizing, skin barrier improvement, and wrinkle improvement. LBA is a next-generation skincare ingredient that could replace AHA and BHA.

 

First
generation
First
generation
Second
generation
Third
generation
Acid AHA
Glycolic acid / Lactic acid
BHA
Salicylic acid
PHA
Gluconolactone
PHA
Lactobionic acid / Maltobionic acid
Molecular size Minimum Small Large Maximum
Irritation (Pain) High High Low Non
Light sensitivity High High Low Non
Hydroxyl group 1 1 4 8

The efficacies of Lactobionic Acid

  • Improvement of skin barrier
  • Exfoliating
  • Moisturizing enhancement
  • Wrinkle improvement
  • TEWL reduction
  • Brightening effect

Improvement of skin barrier function

Using 3D-skin Keraskin, a human skin model observing the expression of Biomarker by IHC

※ Positive Biomarker : Keratin 10 , Loricrine , Filaggrin , Claudin-1

Loricrin

Filaggrin

Claudin-1

Keratin 10

Laboratory (LCS Biotech) conducted skin segmentation and barrier function tests of AHA, BHA, and PHA (Lactobionic Acid), iwas confirmed that PHA (Lactobionic Acid) had superior Biomarker expression and enhanced skin barrier compared to other Hydroxy Acids.

Human Clinical Test Result

Comparison of skin improvement rate with 2 weeks use of cream containing 3% BioLactobionic Acid compared to the control cream

Comparison of wrinkle improvement rate with 4 weeks use of cream containing 8% BioLactobionic Acid compared to the control cream

Human clinical test has confirmed that the test cream containing BioLactobionic Acid has moisturizing effect, exfoliation effect, TEWL reduction, and anti-wrinkle effect compared to the control cream (P&K Skin Research Center)

BioLactobionic Acid’s Differentiation

  • The 100% natural Lactobionic Acid produced by GF Fermentech’s proprietary bio-conversion technology and advanced purification technology

  • No preservative, No chemical, No organic solvent, Non-GMO PHA

  • Ingredients with 95% or more purity

  • Human skin irritation test completed

  • Skin moisturization, exfoliation effect, TEWL reduction and anti-wrinkle effect verified by human clinical study

  • INCI Registered (Skin conditioning agent and pH adjusters)

  • COSMOS/ECOCERT Certified (Peeling agent and pH adjusters)

BioLactobionic Acid Leaflet Download

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